The ingredient, explained
Acetyl Hexapeptide-8
Selected evidence concerns human topical trial.
Ingredient guide
What it is and what it does
About this ingredient: Official product ingredient declaration ↗
- Peptide
- An ingredient made from linked amino-acid units. The peptide name identifies a particular material, not a shared clinical effect for all peptides.
Function definitions: European Commission: Cosmetic peptide nomenclature ↗
A closer look
What the research shows
Human topical research
Periorbital wrinkles and skin-replica roughness improved in the Argireline group compared with placebo after four weeks.
What this does not tell us
Short study in 60 Chinese participants. Abstract does not establish concentration, blinded design or long-term safety; no comparison with injected treatments.
Sources for this summary. PubMed 23417317 ↗
Research review checked Oct 1, 2026
Bounded review of 1 local candidate titles, selected relevant local abstracts, and targeted primary-source web searches. Not an exhaustive systematic review.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Human topical research · n=60
The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study. ↗
American journal of clinical dermatology · 2013
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
- INCI name on ingredient lists
- ACETYL HEXAPEPTIDE-8
Other recorded names (2)
- acetyl hexapeptide-3
- argireline
Sources for this ingredient record
- Official product ingredient declaration ↗ · Recorded Aug 10, 2026