The ingredient, explained
Alpha-isomethyl Ionone
Alpha-Isomethyl Ionone has published research relevant to the stated experimental context.
Ingredient guide
What it is and what it does
3-Methyl-4--2‚6,6-trimethyl-2-cyclohexenyl--3-buten-2-one
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Perfuming
- A formulation role for perfume and aromatic raw materials that give a product its scent.
- Skin conditioning
- A broad cosmetic role for maintaining skin condition. It does not identify a particular clinical benefit.
Function definitions: Danish Environmental Protection Agency: Cosmetic fragrance functions ↗ · European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Human safety research
Patch testing of people with suspected cosmetic contact dermatitis found positive responses to alpha-isomethyl-ionone and other specific fragrances.
What this does not tell us
Selected patients with suspected dermatitis, not the general cosmetic-using population. Sample size and concentration are not in the reviewed abstract, so no prevalence estimate is assigned.
Sources for this summary. PubMed 16364118 ↗
Research review checked Oct 1, 2026
Selective exact-identity review of 0 supplied local candidates and the targeted primary-source search recorded below. Bounded review, not a systematic search.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Human safety research
Fragrance contact dermatitis in Korea: a joint study. ↗
Contact dermatitis · 2005
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
3-Methyl-4--2‚6,6-trimethyl-2-cyclohexenyl--3-buten-2-one
- INCI name on ingredient lists
- ALPHA-ISOMETHYL IONONE
- CAS registry number
- 127-51-5
- EC number
- 204-846-3
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026



