The ingredient, explained
Ascorbyl Tetraisopalmitate
Selected evidence concerns human topical combination.
Ingredient guide
What it is and what it does
L-ascorbic acid, tetraisohexadecanoate
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Emollient
- Helps soften and smooth the skin surface.
- Antioxidant
- Limits oxidation, including deterioration of formulation ingredients. This label alone does not show a clinical antioxidant effect in skin.
- Skin conditioning
- A broad cosmetic role for maintaining skin condition. It does not identify a particular clinical benefit.
Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Human research on a combination
Combined regimens increased hydration and dermal echogenicity, with pigmentation and epidermal-renewal changes.
What this does not tell us
Sixty women aged 20 to 30; sunscreen and rice peptides were included. Contribution of ascorbyl tetraisopalmitate alone and duration are not established by the abstract.
Sources for this summary. PubMed 33529350 ↗
Research review checked Oct 1, 2026
Bounded review of 0 local candidate titles, selected relevant local abstracts, and targeted primary-source web searches. Not an exhaustive systematic review.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Human research on a combination · n=60
Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study. ↗
Photochemistry and photobiology · 2021
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
L-ascorbic acid, tetraisohexadecanoate
- INCI name on ingredient lists
- ASCORBYL TETRAISOPALMITATE
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026


