The ingredient, explained
Ceramide 1
Ceramide 1 has published research relevant to the stated experimental context.
Ingredient guide
What it is and what it does
Ceramide 1 -Retired- is the N-acylated phytosphingosine having the erythro structure that conforms generally to the formula, where n has a value ranging from 10 to 20. The INCI Name, Ceramide 1, originally developed in 1997, was designated with a retired status in 2014. For an interim period of time, trade name assignments formerly published with the INCI Name Ceramide 1 will be retained in the retired monograph, and also published with the new name assignment, Ceramide EOP.
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Hair conditioning
- Improves cosmetic hair properties such as softness, shine or combability.
- Skin conditioning
- A broad cosmetic role for maintaining skin condition. It does not identify a particular clinical benefit.
Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Human research on a combination
The combined cream improved hydration, water loss and skin pH compared with hydrophilic cream after 28 days, with some effects persisting after discontinuation.
What this does not tell us
Three ceramides and a complete formulation prevent isolating ceramide 1. Trial involved 24 subjects with senile xerosis and lower-leg application.
Sources for this summary. PubMed 31585489 ↗
Research review checked Oct 1, 2026
Selective exact-identity review of 1 supplied local candidates and the targeted primary-source search recorded below. Bounded review, not a systematic search.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Human research on a combination · n=24
The 24-hr, 28-day, and 7-day post-moisturizing efficacy of ceramides 1, 3, 6-II containing moisturizing cream compared with hydrophilic cream on skin dryness and barrier disruption in senile xerosis treatment. ↗
Dermatologic therapy · 2019
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
Ceramide 1 -Retired- is the N-acylated phytosphingosine having the erythro structure that conforms generally to the formula, where n has a value ranging from 10 to 20. The INCI Name, Ceramide 1, originally developed in 1997, was designated with a retired status in 2014. For an interim period of time, trade name assignments formerly published with the INCI Name Ceramide 1 will be retained in the retired monograph, and also published with the new name assignment, Ceramide EOP.
- INCI name on ingredient lists
- CERAMIDE 1
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026