The ingredient, explained
Chlorhexidine Digluconate
Chlorhexidine Digluconate has published research relevant to the stated experimental context.
Ingredient guide
What it is and what it does
D-Gluconic acid, compound with N,N''-bis-4-chlorophenyl--3‚12-diimino-2‚4,11‚13-tetraazatetradecanediamidine -2:1-
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Antimicrobial
- A technical role associated with controlling microorganisms on skin.
- Oral care
- Supports cosmetic functions in the mouth, such as cleaning or deodorising.
- Preservative
- Helps inhibit microbial growth in the cosmetic product.
Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Human safety research
The tested scrub failed the study's surgical hand antisepsis efficacy criterion and did not lower hand bacterial load under these conditions.
What this does not tell us
Specific surgical scrub protocol and comparator concentrations; this negative result does not characterize all formulations or cosmetic skin benefits.
Sources for this summary. PubMed 30334981 ↗
Research review checked Oct 1, 2026
Selective exact-identity review of 1 supplied local candidates and the targeted primary-source search recorded below. Bounded review, not a systematic search.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Human safety research
Effectiveness of surgical hand antisepsis using chlorhexidine digluconate and parachlorometaxylenol hand scrub: Cross-over trial. ↗
Medicine · 2018
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
D-Gluconic acid, compound with N,N''-bis-4-chlorophenyl--3‚12-diimino-2‚4,11‚13-tetraazatetradecanediamidine -2:1-
- INCI name on ingredient lists
- CHLORHEXIDINE DIGLUCONATE
- CAS registry number
- 18472-51-0
- EC number
- 242-354-0
Other recorded names (2)
- chlorhexidine gluconate
- chlorhexidini gluconati solutio
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026


