The ingredient, explained
Chloroxylenol
Research examined CHLOROXYLENOL under the stated study conditions.
Ingredient guide
What it is and what it does
Phenol, 4-chloro-3‚5-dimethyl-
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Antimicrobial
- A technical role associated with controlling microorganisms on skin.
- Deodorant
- Helps reduce or mask unwanted body odour.
- Preservative
- Helps inhibit microbial growth in the cosmetic product.
Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Human topical treatment study
Chloroxylenol and zinc oxide cream reduced acne lesion counts more than its vehicle.
What this does not tell us
41 completed, 8 weeks, two active ingredients. Similar results to benzoyl peroxide do not prove equivalence or isolate chloroxylenol. Medical acne treatment does not establish general cosmetic benefit.
Sources for this summary. PubMed 10671963 ↗
Research review checked Oct 1, 2026
Review supplied candidate titles and available abstracts selectively for exact identity; targeted primary PubMed/publisher searches. This is not an exhaustive systematic review.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Human topical treatment study · n=41
Chloroxylenol and zinc oxide containing cream (Nels cream) vs. 5% benzoyl peroxide cream in the treatment of acne vulgaris. A double-blind, randomized, controlled trial. ↗
Clinical and experimental dermatology · 2000
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
Phenol, 4-chloro-3‚5-dimethyl-
- INCI name on ingredient lists
- CHLOROXYLENOL
- CAS registry number
- 88-04-0, 1321-23-9
- EC number
- 201-793-8 / 215-316-6
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026
