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The ingredient, explained

Citrulline

L-Ornithine, N-5---aminocarbonyl--

Skin conditioning
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Ingredient guide

What it is and what it does

About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗

Skin conditioning
A broad cosmetic role for maintaining skin condition. It does not identify a particular clinical benefit.

Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗

Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.

A closer look

What the research shows

Local papers concern plasma biomarkers, blood pressure or autoimmune serology, not an applied exact ingredient with skin outcomes. Targeted primary search found tripeptide-10-citrulline, a different peptide, and oral cardiovascular studies. The 21-amino-acid cosmetic assessment does not name citrulline. No qualifying exact skin/cosmetic study established in this bounded search.

Research review checked Oct 1, 2026

Read exact local candidate abstracts first; select identity-relevant papers; targeted primary PubMed/publisher searches. This is not an exhaustive systematic review.

Ingredient research is not proof that a product containing this ingredient works.

Follow the formula

Products containing this ingredient

All 2 products ↗

From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.

Names and identifiers

INCI name on ingredient lists
CITRULLINE
CAS registry number
372-75-8
EC number
206-759-6

Sources for this ingredient record