The ingredient, explained

Cyclopentasiloxane

Cyclopentasiloxane has published research relevant to cosmetic safety assessment.

Ingredient guide

What it is and what it does

Cyclopentasiloxane, also called D5, is a volatile cyclic silicone. It spreads readily over skin and hair and then evaporates, making it useful as a carrier and texture ingredient in cosmetic formulas.

About this ingredient: European Commission: Cyclopentasiloxane identity and opinion ↗

A verified formulation role is not on file for this name.

Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.

A closer look

What the research shows

Safety assessment

The assessment combined exposure estimates, Monte Carlo analysis and a physiologically based pharmacokinetic model to compare internal doses with toxicological benchmarks.

What this does not tell us

This is a modeled human health risk assessment, not a clinical skin-benefit trial. Conclusions depend on the exposure assumptions and toxicological benchmarks; environmental or current regulatory status is not assessed here.

Sources for this summary. PubMed 26577197 ↗

Research review checked Oct 1, 2026

Selective exact-identity review of 0 supplied local candidates and the targeted primary-source search recorded below. Bounded review, not a systematic search.

Ingredient research is not proof that a product containing this ingredient works.