The ingredient, explained
Glycol
Glycol has published research relevant to the stated experimental context.
Ingredient guide
What it is and what it does
Ethane-1‚2-diol, Ethylene glycol
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Humectant
- Helps attract and retain moisture.
- Viscosity controlling
- Adjusts how thick or fluid a product is.
- Solvent
- Dissolves other ingredients in a formula.
Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Research review
The review describes route-dependent absorption and metabolism, including systemic toxicity after ingestion and relatively limited dermal absorption.
What this does not tell us
Toxicology review for intended chemical applications, not a cosmetic efficacy trial or a blanket topical safety promise. Ethylene glycol is distinct from glycolic acid and propylene glycol.
Sources for this summary. PubMed 28689762 ↗
Research review checked Oct 1, 2026
Selective exact-identity review of 10 supplied local candidates and the targeted primary-source search recorded below. Bounded review, not a systematic search.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Research review
A toxicological review of the ethylene glycol series: Commonalities and differences in toxicity and modes of action. ↗
Toxicology letters · 2017
Follow the formula
Products containing this ingredient
From the Serenfold edit. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
Ethane-1‚2-diol, Ethylene glycol
- INCI name on ingredient lists
- GLYCOL
- CAS registry number
- 107-21-1
- EC number
- 203-473-3
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026
