The ingredient, explained
Glycolic Acid
An exfoliating acid studied in leave-on creams and much stronger short-contact peels.
Ingredient guide
What it is and what it does
Acetic acid, hydroxy-
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- AHA exfoliant
- Alpha hydroxy acid category. Exfoliation depends on the acid, concentration, pH and the rest of the formula; an AHA may also be used to control pH.
- Buffering
- Helps resist changes in a formula's pH.
Function definitions: FDA: Alpha hydroxy acids ↗ · European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Human topical research
In a 74-woman, 22-week vehicle-controlled trial, 8% glycolic acid cream produced modest improvements in facial photodamage. A separate 41-volunteer study reported improvements in texture and fine wrinkling after weekly five-minute applications of a 50% peel for four weeks.
What this does not tell us
The concentration, acidity, vehicle and contact time differ markedly between these studies. Peel outcomes cannot be transferred to a lower-strength daily product. One participant withdrew from the cream trial because of irritation.
Sources for this summary. PubMed 8651713 ↗PubMed 8634809 ↗
Research review checked Sep 30, 2026
Selected primary sources were reviewed for the existing research brief on 30 September 2026, with exact ingredient, route and combination limitations recorded. This was a bounded editorial review, not a systematic search.
Ingredient research is not proof that a product containing this ingredient works.
Read the 2 selected studies
Human topical research · n=74
Topical 8% glycolic acid and 8% L-lactic acid creams for the treatment of photodamaged skin. A double-blind vehicle-controlled clinical trial. ↗
Archives of dermatology · 1996
Human topical research · n=41
Clinical improvement of photoaged skin with 50% glycolic acid. A double-blind vehicle-controlled study. ↗
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 1996
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
Acetic acid, hydroxy-
- INCI name on ingredient lists
- GLYCOLIC ACID
- CAS registry number
- 79-14-1
- EC number
- 201-180-5
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026

