The ingredient, explained
Glycyrrhetinic Acid
Glycyrrhetinic Acid has published research relevant to cosmetic safety assessment.
Ingredient guide
What it is and what it does
Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, -3.beta., 20.beta.--
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Skin conditioning
- A broad cosmetic role for maintaining skin condition. It does not identify a particular clinical benefit.
Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Safety assessment
The assessment relates ingredient purity, dermal tests and systemic toxicology to cosmetic concentrations of glycyrrhetinic acid and specified relatives.
What this does not tell us
Historical group safety assessment, not an efficacy trial or evidence for arbitrary licorice extracts. High-dose systemic findings must not be transferred unqualified to topical cosmetics.
Sources for this summary. PubMed 17613133 ↗
Research review checked Oct 1, 2026
Selective exact-identity review of 1 supplied local candidates and the targeted primary-source search recorded below. Bounded review, not a systematic search.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Safety assessment
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate, and Potassium Glycyrrhizinate. ↗
International journal of toxicology · 2007
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, -3.beta., 20.beta.--
- INCI name on ingredient lists
- GLYCYRRHETINIC ACID
- CAS registry number
- 471-53-4
- EC number
- 207-444-6
Other recorded names (1)
- enoxolone
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026