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The ingredient, explained

Hexylene Glycol

A published safety assessment explicitly covers HEXYLENE GLYCOL.

EmulsifyingPerfumingSkin conditioningSurfactantSolvent
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Ingredient guide

What it is and what it does

2-Methylpentane-2‚4-diol

About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗

Emulsifying
Helps liquids that do not normally mix form a mixture.
Perfuming
A formulation role for perfume and aromatic raw materials that give a product its scent.
Skin conditioning
A broad cosmetic role for maintaining skin condition. It does not identify a particular clinical benefit.
Surfactant
Changes surface tension to help a product distribute or interact with other materials.
Solvent
Dissolves other ingredients in a formula.

Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗ · Danish Environmental Protection Agency: Cosmetic fragrance functions ↗

Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.

A closer look

What the research shows

Safety assessment

The assessment examined low systemic toxicity and skin irritation; hexylene glycol caused moderate rabbit skin irritation.

What this does not tell us

Published safety assessment, not an efficacy trial. Its conclusion is limited to the reported cosmetic uses and concentrations, and relies partly on group read-across where individual data are missing. It does not establish current regulatory status or guarantee tolerance for every formulation. Historical report; formulation and concentration affect local irritation.

Sources for this summary. DOI 10.3109/10915818509078692 ↗

Research review checked Oct 1, 2026

Read exact local candidate abstracts first; select identity-relevant papers; targeted primary PubMed/publisher searches. This is not an exhaustive systematic review.

Ingredient research is not proof that a product containing this ingredient works.

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Products containing this ingredient

All 130 products ↗

From the Serenfold edit. Linked by the ingredient list, without an efficacy ranking.

Names and identifiers

Registry identity

2-Methylpentane-2‚4-diol

INCI name on ingredient lists
HEXYLENE GLYCOL
CAS registry number
107-41-5
EC number
203-489-0

Sources for this ingredient record