The ingredient, explained
Hydroxyacetophenone
Hydroxyacetophenone has published research relevant to the stated experimental context.
Ingredient guide
What it is and what it does
Ethanone, 1--4-hydroxyphenyl--,p-Hydroxyacetophenone
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Antioxidant
- Limits oxidation, including deterioration of formulation ingredients. This label alone does not show a clinical antioxidant effect in skin.
Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Human safety research
The published case report documents contact dermatitis attributed to hydroxyacetophenone and flare-up during repeated open application testing.
What this does not tell us
No abstract is available. Details beyond the title, indexed case-report classification and chemical identity remain unverified. A case report cannot estimate risk frequency.
Sources for this summary. PubMed 36718024 ↗
Research review checked Oct 1, 2026
Selective exact-identity review of 0 supplied local candidates and the targeted primary-source search recorded below. Bounded review, not a systematic search.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Human safety research
Allergic contact dermatitis from hydroxyacetophenone in an anti-wrinkle facial serum with flare-up reactions triggered by the repeated open application test. ↗
Contact dermatitis · 2023
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
Ethanone, 1--4-hydroxyphenyl--,p-Hydroxyacetophenone
- INCI name on ingredient lists
- HYDROXYACETOPHENONE
- CAS registry number
- 99-93-4
- EC number
- 202-802-8
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026


