The ingredient, explained
Hydroxyapatite
A primary study examines this ingredient in the specified preparation and setting.
Ingredient guide
What it is and what it does
Hydroxylapatite -Ca5-OH--PO4-3-
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Abrasive
- Provides mechanical surface cleaning or polishing.
- Bulking
- Changes a product's bulk density.
- Emulsion stabilising
- Helps keep an emulsion from separating.
Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Human topical treatment study
Biomaterial did not significantly speed re-epithelialization versus standard secondary-intention wound care, but reduced pain and measured skin thickness.
What this does not tell us
Mixture and medical surgical defects; no isolated hydroxyapatite effect. Hydroxyapatite present in both arms of separate injected-hand-filler study, so not selected for differential efficacy.
Sources for this summary. PubMed 37647156 ↗
Research review checked Oct 1, 2026
Bounded review of local candidates, exact-name indexed primary journal/PubMed safety and topical searches; not a systematic review.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Human topical treatment study · n=37
Novel Biomaterial Containing Gelatin, Manuka Honey, and Hydroxyapatite Enhanced Secondary Intention Healing Versus Standard Secondary Intention Healing in Mohs Surgical Defects on the Head and Distal Lower Extremities-A Randomized Controlled Trial: Pilot Study. ↗
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2023
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
Hydroxylapatite -Ca5-OH--PO4-3-
- INCI name on ingredient lists
- HYDROXYAPATITE
- CAS registry number
- 1306-06-5
- EC number
- 215-145-7
Other recorded names (1)
- durapatite
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026



