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The ingredient, explained

Isobutylamido Thiazolyl Resorcinol

Research examined ISOBUTYLAMIDO THIAZOLYL RESORCINOL under the stated study conditions.

Bleaching
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Ingredient guide

What it is and what it does

Propanamide, N-[4--2‚4-dihydroxyphenyl--2-thiazolyl]-2-methyl-

About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗

Bleaching
A technical role associated with lightening hair or skin.

Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗

Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.

A closer look

What the research shows

Human topical treatment study

Both 0.2% Thiamidol and 4% hydroquinone improved melasma measures; between-group differences were not significant.

What this does not tell us

50 women randomized, 49 completed, 90 days and tinted SPF 60 sunscreen in both groups. No vehicle comparison and no formal equivalence established. Two Thiamidol recipients developed allergic contact dermatitis.

Sources for this summary. PubMed 33988887 ↗

Research review checked Oct 1, 2026

Review supplied candidate titles and available abstracts selectively for exact identity; targeted primary PubMed/publisher searches. This is not an exhaustive systematic review.

Ingredient research is not proof that a product containing this ingredient works.

Read the 1 selected study

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Products containing this ingredient

All 1 products ↗

From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.

Names and identifiers

Registry identity

Propanamide, N-[4--2‚4-dihydroxyphenyl--2-thiazolyl]-2-methyl-

INCI name on ingredient lists
ISOBUTYLAMIDO THIAZOLYL RESORCINOL
CAS registry number
1428450-95-6

Sources for this ingredient record