The ingredient, explained

Isododecane

A published safety assessment explicitly covers ISODODECANE.

EmollientPerfumingSolvent

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Ingredient guide

What it is and what it does

2‚2,4‚6,6-Pentamethylheptane; Hydrocarbons, C4, 1‚3-butadiene-free, polymd., triisobutylene fraction, hydrogenated

About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗

Emollient: Helps soften and smooth the skin surface.
Perfuming: A formulation role for perfume and aromatic raw materials that give a product its scent.
Solvent: Dissolves other ingredients in a formula.

Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗ · Danish Environmental Protection Agency: Cosmetic fragrance functions ↗

Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.

A closer look

What the research shows

Safety assessment

The panel accepted the reported cosmetic-use conditions after animal and clinical toxicity review.

What this does not tell us

Published safety assessment, not an efficacy trial. Its conclusion is limited to the reported cosmetic uses and concentrations, and relies partly on group read-across where individual data are missing. It does not establish current regulatory status or guarantee tolerance for every formulation. Solvent composition and exposure route matter; cosmetic dermal use does not establish inhalation or oral safety.

Sources for this summary. DOI 10.1177/1091581812463087 ↗

Research review checked Oct 1, 2026

Read exact local candidate abstracts first; select identity-relevant papers; targeted primary PubMed/publisher searches. This is not an exhaustive systematic review.

Review source 1 ↗

Ingredient research is not proof that a product containing this ingredient works.

Read the 1 selected study

Safety assessment
Safety assessment of isoparaffins as used in cosmetics. ↗
International journal of toxicology · 2012

Follow the formula

Products containing this ingredient

All 99 products ↗

From the Serenfold edit. Linked by the ingredient list, without an efficacy ranking.

Clinique

Take The Day Off Makeup Remover For Lids, Lashes and Lips

Eye care · 10 linked ingredients

Inside the formula

Names and identifiers

Registry identity