The ingredient, explained

Isoleucine

Isoleucine has published research relevant to the stated experimental context.

AntistaticHair conditioningSkin conditioning

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Ingredient guide

What it is and what it does

L-Isoleucine; DL-allo-Isoleucine; 2-Amino-3-methylpentanoic acid

About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗

Antistatic: Reduces the build-up of static electrical charge on surfaces.
Hair conditioning: Improves cosmetic hair properties such as softness, shine or combability.
Skin conditioning: A broad cosmetic role for maintaining skin condition. It does not identify a particular clinical benefit.

Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗

Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.

A closer look

What the research shows

Human research on a combination

The combination improved facial eczema severity more than the emollient comparator over six weeks in 107 children.

What this does not tell us

Assessor-blinded combination trial does not isolate isoleucine, nor establish oral or routine cosmetic efficacy.

Sources for this summary. PubMed 24750568 ↗

Research review checked Oct 1, 2026

Selective exact-identity review of 3 supplied local candidates and the targeted primary-source search recorded below. Bounded review, not a systematic search.

Review source 1 ↗

Ingredient research is not proof that a product containing this ingredient works.

Read the 1 selected study

Human research on a combination · n=107
Local rhamnosoft, ceramides and L-isoleucine in atopic eczema: a randomized, placebo controlled trial. ↗
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2014

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