The ingredient, explained
Isosorbide Dicaprylate
A primary study examines this ingredient in the specified preparation and setting.
Ingredient guide
What it is and what it does
Isosorbide Dicaprylate is the diester of isosorbide and caprylic acid
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Skin conditioning
- A broad cosmetic role for maintaining skin condition. It does not identify a particular clinical benefit.
Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Human topical treatment study
Diester combination improved itch and reduced relative skin S. aureus abundance versus oatmeal vehicle. EASI 75 difference not significant; hydration/TEWL unchanged.
What this does not tell us
Two diesters, no isolated dicaprylate effect. Mild/moderate adult AD and shared oatmeal; not coconut/sunflower oil trial.
Sources for this summary. PubMed 38394048 ↗
Research review checked Oct 1, 2026
Bounded review of local candidates, exact-name indexed primary journal/PubMed safety and topical searches; not a systematic review.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Human topical treatment study · n=32
Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis. ↗
Dermatitis : contact, atopic, occupational, drug · 2024
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
Isosorbide Dicaprylate is the diester of isosorbide and caprylic acid
- INCI name on ingredient lists
- ISOSORBIDE DICAPRYLATE
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026



