The ingredient, explained
Mannose
A primary study examines this ingredient in the specified preparation and setting.
Ingredient guide
What it is and what it does
D-mannose
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Humectant
- Helps attract and retain moisture.
Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Human oral care research
Mannose-calcium propionate mixture shortened bleeding and healing measures relative to mannose alone.
What this does not tell us
Combination efficacy cannot be assigned to mannose alone; 25 subjects, experimental incisions and short scar follow-up. Cosmetic uninjured-skin use not established.
Sources for this summary. PubMed 40906289 ↗
Research review checked Oct 1, 2026
Bounded review of local candidates, exact-name indexed primary journal/PubMed safety and topical searches; not a systematic review.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Human oral care research · n=25
Rapid and Esthetic Wound Healing in Surgery by Applying a Powdered Mixture of Mannose and Calcium Propionate. ↗
Aesthetic plastic surgery · 2025
Follow the formula
Products containing this ingredient
From the Serenfold edit. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
D-mannose
- INCI name on ingredient lists
- MANNOSE
- CAS registry number
- 3458-28-4
- EC number
- 222-392-4
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026
