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The ingredient, explained

Natamycin

A large randomized trial examined natamycin for fungal corneal ulcers.

AntimicrobialPreservative
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Ingredient guide

What it is and what it does

6‚11‚28-Trioxatricyclo[22.3.1.05‚7]octacosa-8‚14‚16‚18‚20-pentaene-25-carboxylic acid, 22-[-3-amino-3‚6-dideoxy-.beta.-D-mannopyranosyl-oxy]-1‚3,26-trihydroxy-12-methyl-10-oxo-, -1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S--

About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗

Antimicrobial
A technical role associated with controlling microorganisms on skin.
Preservative
Helps inhibit microbial growth in the cosmetic product.

Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗

Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.

A closer look

What the research shows

Human eye treatment study

It outperformed voriconazole on disease-specific outcomes.

What this does not tell us

Eye-infection therapy does not establish cosmetic skin benefit.

Sources for this summary. PubMed 23710492 ↗

Research review checked Oct 1, 2026

Review supplied candidate titles and available abstracts selectively for exact identity; targeted primary PubMed/publisher searches. This is not an exhaustive systematic review.

Ingredient research is not proof that a product containing this ingredient works.

Read the 1 selected study

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Products containing this ingredient

All 1 products ↗

From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.

Names and identifiers

Registry identity

6‚11‚28-Trioxatricyclo[22.3.1.05‚7]octacosa-8‚14‚16‚18‚20-pentaene-25-carboxylic acid, 22-[-3-amino-3‚6-dideoxy-.beta.-D-mannopyranosyl-oxy]-1‚3,26-trihydroxy-12-methyl-10-oxo-, -1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S--

INCI name on ingredient lists
NATAMYCIN
CAS registry number
7681-93-8
EC number
231-683-5 I

Sources for this ingredient record