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The ingredient, explained

Nicotinamide Adenine Dinucleotide

An uncontrolled melasma series examined microneedling followed by NAD+ booster.

Skin conditioning
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Ingredient guide

What it is and what it does

Adenosine 5'--trihydrogen diphosphate-, 5'->5'-ester with 3--aminocarbonyl--1-beta-D-ribofuranosylpyridinium hydroxide, inner salt

About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗

Skin conditioning
A broad cosmetic role for maintaining skin condition. It does not identify a particular clinical benefit.

Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗

Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.

A closer look

What the research shows

Human topical treatment study

Pigmentation scores improved during the combined procedure.

What this does not tell us

No control and procedural delivery prevent attribution to routine topical NAD alone.

Sources for this summary. PubMed 41870519 ↗

Research review checked Oct 1, 2026

Review supplied candidate titles and available abstracts selectively for exact identity; targeted primary PubMed/publisher searches. This is not an exhaustive systematic review.

Ingredient research is not proof that a product containing this ingredient works.

Read the 1 selected study

Follow the formula

Products containing this ingredient

All 1 products ↗

From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.

Names and identifiers

Registry identity

Adenosine 5'--trihydrogen diphosphate-, 5'->5'-ester with 3--aminocarbonyl--1-beta-D-ribofuranosylpyridinium hydroxide, inner salt

INCI name on ingredient lists
NICOTINAMIDE ADENINE DINUCLEOTIDE
CAS registry number
53-84-9
EC number
200-184-4
Other recorded names (1)
  • nadide

Sources for this ingredient record