The ingredient, explained

Nonapeptide-1

A primary study examines this ingredient in the specified preparation and setting.

Hair conditioningSkin conditioning

Ingredient guide

What it is and what it does

Nonapeptide-1 is a synthetic nonapeptide derived from arginine, lysine, methionine, phenylalanine, proline, tryptophan and valine

About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗

Hair conditioning: Improves cosmetic hair properties such as softness, shine or combability.
Skin conditioning: A broad cosmetic role for maintaining skin condition. It does not identify a particular clinical benefit.

Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗

Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.

A closer look

What the research shows

Human research on a combination

Maintenance mixture showed improving melasma measures but differences from sunscreen control did not reach statistical significance.

What this does not tell us

Mixture after shared triple-combination therapy. Small trial; no isolated peptide effect. Eight months includes multiple phases and follow-up, not peptide treatment duration.

Sources for this summary. PubMed 34379946 ↗

Research review checked Oct 1, 2026

Bounded review of local candidates, exact-name indexed primary journal/PubMed safety and topical searches; not a systematic review.

Ingredient research is not proof that a product containing this ingredient works.