The ingredient, explained
Oxidized Glutathione
A small trial tested topical oxidized glutathione.
Ingredient guide
What it is and what it does
bi-glutathion-S-yl-
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Emollient
- Helps soften and smooth the skin surface.
- Skin conditioning
- A broad cosmetic role for maintaining skin condition. It does not identify a particular clinical benefit.
Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Human topical research
The 2% lotion reduced melanin-index measurements compared with placebo.
What this does not tell us
Thirty women and ten weeks cannot establish durable effects or broader glutathione preparations.
Sources for this summary. PubMed 25378941 ↗
Research review checked Oct 1, 2026
Read exact local candidate abstracts first; select identity-relevant papers; targeted primary PubMed/publisher searches. This is not an exhaustive systematic review.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Human topical research · n=30
Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women. ↗
Clinical, cosmetic and investigational dermatology · 2014
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
bi-glutathion-S-yl-
- INCI name on ingredient lists
- OXIDIZED GLUTATHIONE
- CAS registry number
- 27025-41-8
- EC number
- 248-170-7
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026