The ingredient, explained
Proline
A published expert assessment examines cosmetic-use safety.
Ingredient guide
What it is and what it does
2-Pyrrolidinecarboxylic acid, -S--
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Hair conditioning
- Improves cosmetic hair properties such as softness, shine or combability.
- Skin conditioning
- A broad cosmetic role for maintaining skin condition. It does not identify a particular clinical benefit.
Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Safety assessment
Proline is explicitly included in the amino-acid group covered by the cosmetic-use safety conclusion.
What this does not tell us
This is an exposure and toxicology assessment. Evidence about a proline derivative or collagen does not establish an isolated topical proline benefit.
Sources for this summary. PubMed 24335967 ↗
Research review checked Oct 1, 2026
Bounded targeted searches for the exact ingredient identity in primary research or final expert assessments, with selected-source verification. Not a systematic review.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Safety assessment
Safety assessment of α-amino acids as used in cosmetics. ↗
International journal of toxicology · 2013
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
2-Pyrrolidinecarboxylic acid, -S--
- INCI name on ingredient lists
- PROLINE
- CAS registry number
- 147-85-3 -L--, 609-36-9 -dl-alpha-
- EC number
- 205-702-2 / 210-189-3
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026


