The ingredient, explained
Squalene
Squalene has published research relevant to cosmetic safety assessment.
Ingredient guide
What it is and what it does
2‚6,10‚15‚19‚23-Hexamethyltetracosa-2‚6,10‚14‚18‚22-hexaene
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Emollient
- Helps soften and smooth the skin surface.
- Antistatic
- Reduces the build-up of static electrical charge on surfaces.
- Hair conditioning
- Improves cosmetic hair properties such as softness, shine or combability.
- Refatting
- Replenishes lipids on hair or the outer skin layers.
- Skin conditioning
- A broad cosmetic role for maintaining skin condition. It does not identify a particular clinical benefit.
Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Safety assessment
The report summarizes animal toxicity and irritation studies and limited human irritation or sensitization testing of squalene-containing formulations.
What this does not tell us
Historical safety assessment, not a clinical benefit trial. The original journal citation is 1982; migrated publisher header shows 1990.
Sources for this summary. DOI 10.3109/10915818209013146 ↗
Research review checked Oct 1, 2026
Selective exact-identity review of 5 supplied local candidates and the targeted primary-source search recorded below. Bounded review, not a systematic search.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Safety assessment
Final Report on the Safety Assessment of Squalane and Squalene ↗
· 1982
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
2‚6,10‚15‚19‚23-Hexamethyltetracosa-2‚6,10‚14‚18‚22-hexaene
- INCI name on ingredient lists
- SQUALENE
- CAS registry number
- 111-02-4
- EC number
- 203-826-1
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026



