The ingredient, explained

Tetrahydrodiferuloylmethane

Laboratory studies examined tetrahydrocurcumin, the exact named compound.

AntioxidantTyrosinase inhibitor / brightening

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Ingredient guide

What it is and what it does

3‚5-Heptanedione, 1‚7-bis-4-hydroxy-3-methoxyphenyl-

About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗

Antioxidant: Limits oxidation, including deterioration of formulation ingredients. This label alone does not show a clinical antioxidant effect in skin.
Tyrosinase inhibitor / brightening: Research category for changes in pigmentation or uneven skin tone. The label does not establish that a finished product changes pigmentation.

Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗ · Original niacinamide study: Pigmentation and hyperpigmented spots ↗

Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.

A closer look

What the research shows

Laboratory research

Cells showed reduced melanin production and oxidative-stress injury.

What this does not tell us

These are laboratory findings and do not demonstrate human brightening or anti-aging effects.

Sources for this summary. PubMed 34452146 ↗

Research review checked Oct 1, 2026

Read exact local candidate abstracts first; select identity-relevant papers; targeted primary PubMed/publisher searches. This is not an exhaustive systematic review.