Everything is connected

← Ingredient index

The ingredient, explained

Tromethamine

A published expert safety assessment covers the exact ingredient in the specified exposure context.

BufferingMasking
Explore connections

Ingredient guide

What it is and what it does

1‚3-Propanediol, 2-amino-2--hydroxymethyl--

About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗

Buffering
Helps resist changes in a formula's pH.
Masking
Reduces or conceals the formula's underlying odour or taste.

Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗

Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.

A closer look

What the research shows

Safety assessment

Panel concluded listed ingredients safe in assessed cosmetic uses and concentrations.

What this does not tell us

Grouped safety assessment uses structural similarity. Ketorolac tromethamine trials study a drug salt, not isolated tromethamine efficacy.

Sources for this summary. PubMed 29761730 ↗

Research review checked Oct 1, 2026

Bounded review of local candidates, exact-name indexed primary journal/PubMed safety and topical searches; not a systematic review.

Ingredient research is not proof that a product containing this ingredient works.

Read the 1 selected study

Follow the formula

Products containing this ingredient

All 176 products ↗

From the Serenfold edit. Linked by the ingredient list, without an efficacy ranking.

Names and identifiers

Registry identity

1‚3-Propanediol, 2-amino-2--hydroxymethyl--

INCI name on ingredient lists
TROMETHAMINE
CAS registry number
77-86-1
EC number
201-064-4
Other recorded names (1)
  • trometamol

Sources for this ingredient record