Human topical research
Microfine zinc oxide is a superior sunscreen ingredient to microfine titanium dioxide.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2000
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Diffuse reflectance spectroscopy measured UVA attenuation on normal human skin. Sample size, treatment duration and randomization were not reported in the abstract.
Checked against the published abstract on Oct 1, 2026. Read the source ↗
Abstract
Background Microfine zinc oxide and microfine titanium dioxide are particulate sunscreen ingredients that absorb broad-spectrum ultraviolet (UV) irradiation.Objective We compare microfine zinc oxide and microfine titanium dioxide for their abilities to attenuate UVA radiation and their relative whiteness in cosmetic formulations.Methods UVA attenuation was measured by diffuse reflectance spectroscopy on normal human skin in vivo. Whiteness was determined by reflectance density of dried coatings on a black background of the two particulates at varying concentrations.Results Microfine zinc oxide demonstrates superior protection compared to microfine titanium dioxide in the UV spectrum between 340 and 380 nm. Microfine zinc oxide is less white than titanium dioxide at all concentrations.Conclusion Microfine zinc oxide is superior to microfine titanium dioxide as a sunscreen ingredient. It is more protective against long-wave UVA and is less white at a given concentration.
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