RIFM fragrance ingredient safety assessment, anethole (isomer unspecified), CAS Registry Number 104-46-1.

What was studied

Assessment supports anethole use under the assessed fragrance exposure conditions. It identifies weak skin-sensitization potential and uses trans-anethole read-across for several endpoints. Indexed primary report text verified; complete live full-text access was limited. Safety depends on exposure assumptions and sensitization-risk controls. The assessed isomer-unspecified material is not proof of universal tolerance, allergy-free use or skin benefit.

Checked against the indexed source text on Oct 1, 2026. Source 1 ↗Source 2 ↗Source 3 ↗