The ingredient, explained
Creatine
Creatine has published research relevant to the stated experimental context.
Ingredient guide
What it is and what it does
Glycine, N--Aminoiminomethyl--N-Methyl-
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Skin conditioning
- A broad cosmetic role for maintaining skin condition. It does not identify a particular clinical benefit.
Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Laboratory and human research
Creatine increased collagen synthesis in cultured fibroblasts; the combined face product improved assessed wrinkles and cheek sagging after 6 weeks.
What this does not tell us
Clinical results concern a combination product in male Caucasian participants and do not isolate creatine. Cell collagen synthesis is not a direct clinical collagen measurement.
Sources for this summary. PubMed 22151935 ↗
Research review checked Oct 1, 2026
Selective exact-identity review of 10 supplied local candidates and the targeted primary-source search recorded below. Bounded review, not a systematic search.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Laboratory and human research · n=43
Dermal penetration of creatine from a face-care formulation containing creatine, guarana and glycerol is linked to effective antiwrinkle and antisagging efficacy in male subjects. ↗
Journal of cosmetic dermatology · 2011
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
Glycine, N--Aminoiminomethyl--N-Methyl-
- INCI name on ingredient lists
- CREATINE
- CAS registry number
- 57-00-1, 6020-87-7
- EC number
- 200-306-6 / -
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026
