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The ingredient, explained

Dimethyl Isosorbide

Dimethyl Isosorbide has published research relevant to the stated experimental context.

Viscosity controllingSolvent
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Ingredient guide

What it is and what it does

1‚4:3‚6-Dianhydro-2‚5-di-O-methyl-D-glucitol

About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗

Viscosity controlling
Adjusts how thick or fluid a product is.
Solvent
Dissolves other ingredients in a formula.

Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗

Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.

A closer look

What the research shows

Human oral care research

The report describes enhanced potassium nitrate permeation and treatment of aphthous stomatitis in the combined delivery system.

What this does not tell us

No extractable sample size, randomization or independent dimethyl isosorbide efficacy is established from the abstract; oral mucosa differs from ordinary skin.

Sources for this summary. PubMed 15000637 ↗

Research review checked Oct 1, 2026

Selective exact-identity review of 4 supplied local candidates and the targeted primary-source search recorded below. Bounded review, not a systematic search.

Ingredient research is not proof that a product containing this ingredient works.

Read the 1 selected study

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Products containing this ingredient

All 43 products ↗

From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.

Names and identifiers

Registry identity

1‚4:3‚6-Dianhydro-2‚5-di-O-methyl-D-glucitol

INCI name on ingredient lists
DIMETHYL ISOSORBIDE
CAS registry number
5306-85-4
EC number
226-159-8

Sources for this ingredient record