The ingredient, explained

Melia Azadirachta Leaf Extract

A leaf-specific study examines responses in cultured skin cells.

Skin conditioning

Explore connections

Ingredient guide

What it is and what it does

Melia Azadirachta Leaf Extract is an extract of the leaves of the Neem Tree, Melia azadirachta L., Meliaceae

About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗

Skin conditioning: A broad cosmetic role for maintaining skin condition. It does not identify a particular clinical benefit.

Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗

Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.

A closer look

What the research shows

Laboratory research

Laboratory work measured gene-expression changes after cultured skin cells were exposed to a neem leaf extract.

What this does not tell us

The tested leaves were heat-treated and extracted in butylene glycol. Gene-expression measurements in cells do not demonstrate visible skin improvement or establish equivalence to every neem extract.

Sources for this summary. PubMed 29322079 ↗

Research review checked Oct 1, 2026

Bounded targeted searches for the exact ingredient identity in primary research or final expert assessments, with selected-source verification. Not a systematic review.

Ingredient research is not proof that a product containing this ingredient works.