The ingredient, explained
Poloxamer 188
A published expert safety assessment covers this exact ingredient.
Ingredient guide
What it is and what it does
Oxirane, methyl-, polymer with oxirane -75;30-
About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗
- Emulsifying
- Helps liquids that do not normally mix form a mixture.
- Surfactant
- Changes surface tension to help a product distribute or interact with other materials.
Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗
Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.
A closer look
What the research shows
Safety assessment
Panel judged assessed poloxamers safe under described cosmetic use, with purification to control unwanted impurities.
What this does not tell us
Dated group read-across; ethylene/propylene oxide and 1,4-dioxane controls are material. Intravenous drug uses and carrier-only curcumin paper cannot establish cosmetic efficacy.
Sources for this summary. PubMed 18830866 ↗
Research review checked Oct 1, 2026
Bounded review of local candidates, exact-name indexed primary journal/PubMed safety and topical searches; not a systematic review.
Ingredient research is not proof that a product containing this ingredient works.
Read the 1 selected study
Safety assessment
Safety assessment of poloxamers 101, 105, 108, 122, 123, 124, 181, 182, 183, 184, 185, 188, 212, 215, 217, 231, 234, 235, 237, 238, 282, 284, 288, 331, 333, 334, 335, 338, 401, 402, 403, and 407, poloxamer 105 benzoate, and poloxamer 182 dibenzoate as used in cosmetics. ↗
International journal of toxicology · 2008
Follow the formula
Products containing this ingredient
From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.
Names and identifiers
Registry identity
Oxirane, methyl-, polymer with oxirane -75;30-
- INCI name on ingredient lists
- POLOXAMER 188
- CAS registry number
- 9003-11-6
Sources for this ingredient record
- EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗ · ODbL 1.0 (Open Beauty Facts database) · Recorded Aug 8, 2026



