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The ingredient, explained

Resveratrol

This compound has been studied in topical acne gels and, as trans-resveratrol, in a trial separating topical from oral use.

AntioxidantSkin protecting
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Ingredient guide

What it is and what it does

1‚3-Benzenediol, 5-[-1E--2--4-Hydroxyphenyl-ethenyl]-

About this ingredient: EU CosIng ingredient registry (via Open Beauty Facts taxonomy) ↗

Antioxidant
Limits oxidation, including deterioration of formulation ingredients. This label alone does not show a clinical antioxidant effect in skin.
Skin protecting
A technical role associated with protecting skin from external factors.

Function definitions: European Commission ingredient function definitions (SCCNFP/0299/00, pages 16 to 20) ↗

Registry functions describe possible formulation roles, not results for a finished product. A dictionary entry is not an approval or a safety assessment.

A closer look

What the research shows

Selected research

A small 20-person acne pilot reported greater lesion improvement on the side treated with resveratrol gel than with its vehicle after 60 days. A later eight-week trial in 134 women found increased cheek and jaw sebum with 1.5% topical trans-resveratrol. A significant wrinkle-score advantage was found only in the combined oral and topical group.

What this does not tell us

The acne pilot used fixed right-versus-left allocation and needs larger confirmation. The later industry-funded trial had 122 completers and changed two participants between analysis groups after stopping capsules. Topical treatment alone did not demonstrate a significant wrinkle advantage, and the oral combination result cannot be attributed to a cream alone.

Sources for this summary. PubMed 21348544 ↗PubMed 41488277 ↗

Research review checked Sep 30, 2026

Selected primary sources were reviewed for the existing research brief on 30 September 2026, with exact ingredient, route and combination limitations recorded. This was a bounded editorial review, not a systematic search.

Ingredient research is not proof that a product containing this ingredient works.

Read the 2 selected studies

Follow the formula

Products containing this ingredient

All 23 products ↗

From the wider catalogue. Linked by the ingredient list, without an efficacy ranking.

Names and identifiers

Registry identity

1‚3-Benzenediol, 5-[-1E--2--4-Hydroxyphenyl-ethenyl]-

INCI name on ingredient lists
RESVERATROL
CAS registry number
501-36-0
EC number
*610-504-8

Sources for this ingredient record