Dimethicone ↗
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isdin
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ISDIN Ureadin Ultra 40 provides intense exfoliation of localised thickened areas such as calluses or nail abnormalities in an easy-to-apply gel-oil formulation. Key ingredients include the unique, stabilised Urea ISDIN® molecule at a 40% concentration. It is a keratolytic (softens and removes the surface layer of dead skin), helping to reduce severely thickened skin. Dimethicone acts as a filmogenic occlusive that retains moisture in the skin and reduces trans-epidermal water loss. Dr Webster’s Recommendation: Ureadin Ultra 40 helps to reduce localised hyperkeratosis, like thickening of the nails (onychogryphosis) as well as calluses. It facilitates the penetration of anti-fungal treatments by smoothing the upper layers of the skin and nails. A gel-oil texture provides an optimum cosmetic effect, facilitating penetration and achieving greater Urea ISDIN stability at 40%. Caution: Should not be applied to the face, mucous membranes, or open wounds.
Description from Dermastore curated catalogue · Recorded Aug 9, 2026. Product claims have not been independently verified.
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