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Fine lines
Explore measurements of facial lines and skin smoothness in trials of specific topical preparations.
A product appears here because its formula contains these ingredients. This is not a claim that the product works or a safety assessment of that product. Products are listed alphabetically.
Explore connectionsIngredients and their research (3)
- Adenosine
A placebo-controlled study in 126 women reported improved eye-area smoothness with adenosine cream and dissolving film. The abstract does not report concentrations, and the delivery systems matter.
- Bakuchiol
A small 12-week trial found reduced wrinkle surface area with 0.5% bakuchiol and 0.5% retinol. It had no vehicle-only group and used different application frequencies, so it does not establish equivalence between the ingredients.
- Retinol
A 26-week trial found that 0.075% retinol cream improved facial wrinkles more often than its vehicle. Some participants withdrew because of irritation; the result is specific to the tested cream.
Products containing these ingredients
Listed alphabetically, without an efficacy ranking.
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