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SkinCeuticals
Serums
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SkinCeuticals Discoloration Defense is a new-generation, multi-phase dark spot corrector serum that helps address melasma and post-inflammatory hyperpigmentation (PIH). Suitable for hyperpigmentation and uneven skin tone. Key ingredients include 3% Tranexamic Acid, a synthetically derived ingredient that assists in inhibiting the release of inflammatory mediators, specifically prostaglandins and arachidonic acid, which are involved in melanogenesis. Studies have also demonstrated its ability to address hard-to-treat forms of hyperpigmentation, including post-acne marks. 1% Kojic Acid is an antioxidant and skin-brightener that helps to inhibit melanin production and treat age spots, post-inflammatory hyperpigmentation, and melasma. 5% Niacinamide, also known as vitamin B3, offers proven skin-brightening benefits. HEPES is a synthetically derived acid that activates natural enzymes in the skin to help break the bonds that bind dead skin cells to the surface for even exfoliation. Fragrance-free. Hydroquinone-free. Dr. Webster’s Recommendation: SkinCeuticals Discoloration Defense is a layerable, daily-use serum that targets dark marks, helping to brighten the skin without aggravating it. Ideal for use post-hydroquinone treatment, or as a standalone home care routine with the inclusion of a SkinCeuticals antioxidant serum and retinoid. Always use a high-factor, broad-spectrum sunscreen to protect and prevent the skin against UV-induced hyperpigmentation. Updated formula 04/2026
Description from Dermastore curated catalogue · Recorded Aug 9, 2026. Product claims have not been independently verified.
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